Term: nivolumab and hyaluronidase

Pronunciation: (nih-VOL-yoo-mab … HY-al-yoo-RAH-nih-days)

Description:

A combination of two drugs used alone or with other drugs to treat adults with certain types of colorectal cancer, esophageal cancer, gastric (stomach) cancer, gastroesophageal junction adenocarcinoma, hepatocellular carcinoma (a type of liver cancer), melanoma, non-small cell lung cancer, renal cell carcinoma (a type of kidney cancer), squamous cell carcinoma of the head and neck, and urothelial carcinoma (a type of cancer in the bladder or urinary tract). Nivolumab binds to a protein called PD-1, which is found on some normal cells and some types of cancer cells. Nivolumab may block PD-1 and help the immune system kill cancer cells. Hyaluronidase allows nivolumab to be given by injection under the skin. Nivolumab and hyaluronidase can be given in less time than nivolumab alone, which is given as an infusion. Also called Opdivo Qvantig.